Ana married Cristobal Colón Toledo about 1548 in Santo Domingo, CAdiz, Andalucia, Spain. Cristobal (son of Duke of Veragua Diego Colón Perestrelo and Duquessa María Loledo Rrojas) was born about 1508 in Burgos, Burgos, Castilla-Leon, Spain; died about 1523. [Group Sheet] [Family Chart]