Luisa married Duke of Veragua Luis Colon Y Moniz Perestrelo in UNKNOWN in Madrid, Madrid, Madrid, Spain. Luis (son of Duke of Veragua Diego Colón Perestrelo and Duquessa María Loledo Rrojas) was born on 19 Feb 1522 in Santo Domingo, CAdiz, Andalucia, Spain; died on 29 Jan 1572 in Oran, Oran, Algeria; was buried in Santo Domingo, Distrito Nacional, Dominican Republic. [Group Sheet] [Family Chart]

1. Juana Colón Caravjal was born about 1541 in Saanto Domingo, CAdiz, Andalucia, Spain; died in Dec 1570 in Madrid, Madrid, Madrid, Spain.
2. Cristobal Colón Carbajal was born about 1565 in Santo Domingo, CAdiz, Andalucia, Spain; died about 1600 in Spain.
3. Petronila Colón Mosquera was born about 1570 in Oran, Oran, Algeria; died about 1651.