María married Duke of Veragua Luis Colon Y Moniz Perestrelo about 1543 in Santo Domingo, Distrito Nacional, Dominican Republic. Luis (son of Duke of Veragua Diego Colón Perestrelo and Duquessa María Loledo Rrojas) was born on 19 Feb 1522 in Santo Domingo, CAdiz, Andalucia, Spain; died on 29 Jan 1572 in Oran, Oran, Algeria; was buried in Santo Domingo, Distrito Nacional, Dominican Republic. [Group Sheet] [Family Chart]

1. Juana Colón Luyano was born about 1541 in Saanto Domingo, CAdiz, Andalucia, Spain; died about 1570 in Spain.
2. Juan Colón Luyando was born about 1544 in Santo Domingo, Distrito Nacional, Dominican Republic; died about 1616.