Manuela married Fernando Fernandez Flores Rosario on 2 May 1727 in San Juan, Puerto Rico, USA. Fernando was born on 28 Sep 1710 in Caguas, Puerto Rico, USA; died on 12 Mar 1768 in El Pinal, Caguas, Puerto Rico, USA. [Group Sheet] [Family Chart]

1. Rosalia Fernández Delrio was born in 1732.
2. Ysabel Fernández Delrio was born in 1735 in Caguas, Puerto Rico, ESP; died before 1773 in Rio Piedras, Puerto Rico, ESP.
3. Luis Fernández Delrio was born in 1737 in Caguas, Puerto Rico, ESP; died on 12 Sep 1742 in Caguas, Puerto Rico, ESP.
4. Francisca Fernández Delrio was born about 1739 in Caguas, Puerto Rico, ESP; died on 13 Oct 1766 in Caguas, Puerto Rico, ESP.
5. Pedro Flores Rio was born on 25 Mar 1740 in Caguas, Puerto Rico, USA; died on 9 Aug 1792 in Caguas, Puerto Rico, USA.
6. Pedro Fernández Delrio was born on 25 Apr 1740 in Caguas, Puerto Rico, ESP; died on 12 Sep 1742 in Caguas, Puerto Rico,ESP.
7. Francisca Flores Rio was born about 1741 in Caguas, Puerto Rico, USA; died on 13 Oct 1766 in Caguas, Puerto Rico, USA.
8. Infant Flores Rio was born on 12 Sep 1742 in Caguas, Puerto Rico, USA; died on 12 Sep 1742 in Caguas, Puerto Rico, USA.
9. Angela Fernandez Delrio was born on 4 Jun 1744 in Caguas, Puerto Rico, ESP.
10. Juana Antonia Flores Rio was born on 3 Jul 1744 in Caguas, Puerto Rico, USA; died on 7 Mar 1768 in Caguas, Puerto Rico, USA.
11. Juan De La Cruz Flores Rio was born on 23 May 1749 in Caguas, Puerto Rico, USA; died on 15 Jul 1792 in Caguas, Puerto Rico, USA.
12. Joseph Flores Rio was born on 14 Oct 1749 in Caguas, Puerto Rico, USA; died on 5 Oct 1757 in Caguas, Puerto Rico, USA.
13. Bartoleme Flores Delrio was born on 24 Aug 1751 in Las Piedras, Las Piedras, Puerto Rico,Province of Spain; died on 4 Aug 1791 in Las Piedras, Las Piedras, Puerto Rico,Province of Spain.
14. Juan Flores Rio was born about 1754 in Caguas, Puerto Rico, USA; died on 3 Oct 1800 in Caguas, Puerto Rico, USA.
15. Joseph De Los Santos Flores Rio was born on 31 Oct 1760 in Caguas, Puerto Rico, USA.
16. Juan De Los Santos Flores Rio was born on 1 Nov 1760 in Caguas, Puerto Rico; died on 18 Jun 1811 in Caguas, Puerto Rico.

Manuela married Fernando Fernandez Flores on 24 Nov 1738 in Las Piedras, Las Piedras, Puerto Rico, USA. Fernando was born in Las Piedras, Las Piedras, Puerto Rico,Province of Spain; died on 12 Mar 1768 in Las Piedras, Las Piedras, Puerto Rico,Province of Spain. [Group Sheet] [Family Chart]

Ciprian married Juana Luyando Delacruz on 27 Aug 1707 in San Juan, San Juan, Puerto Rico, Puerto Rico, Province of Spain. Juana (daughter of Matias Luyando and Juana Delacruz) was born in 1687 in San Juan, San Juan, Puerto Rico, Puerto Rico, Province of Spain; died in UNKNOWN. [Group Sheet] [Family Chart]

Toribio married Catalina Velasco. Catalina was born in UNKNOWN; died in UNKNOWN. [Group Sheet] [Family Chart]

Matias married Juana Delacruz. Juana was born about 1660 in San Juan, Puerto Rico, Province of Spain. [Group Sheet] [Family Chart]