William married Susannah Owens Briscoe in 1700 in Trinity Parish, Charles, Maryland, United States. Susannah was born in 1687 in Charles, Maryland, United States; died on 11 Feb 1739 in Charles, Maryland, United States. [Group Sheet] [Family Chart]

1. Edmund Howard Compton
2. Alexander Compton
3. John Compton was born on 9 Nov 1702 in Trinity Parish, Charles, Maryland, United States; died in 1714 in Maryland, United States.
4. Philip Compton was born on 5 Jan 1705 in Charles, Maryland, United States; died in 1744.
5. Susanna Compton was born on 2 Jun 1707 in Lancaster, Lancaster, Virginia, United States; died in 1807 in Virginia, USA.
6. Matthew Compton was born on 26 Jun 1709 in Trinity Parish, Charles, Maryland, United States; died on 14 Mar 1770 in Trinity Parish, Charles, Maryland, United States.
7. Eleanor Compton was born on 2 Dec 1711 in Trinity Parish, Charles, Maryland, United States; died on 6 Dec 1783 in Charles, Maryland, United States.
8. Zachariah Compton was born in 1712 in Charles, Maryland, United States; died in 1790 in Culpepper, Virginia, United States.
9. Sarah Compton was born on 24 Mar 1713 in Charles, Maryland, United States; died in 1747.
10. Samuel Compton was born on 19 May 1716 in Trinity Parish, Charles, Maryland, United States; died in 1765 in Charles, Maryland, United States.
11. William Clark Compton was born in 1723 in Charles, Maryland, United States; died in 1808 in Culpeper, Culpeper, Virginia, United States.
12. John Compton was born on 1 Feb 1726 in Charles, Maryland, United States; died on 16 Jan 1797 in Fairfax, Fairfax, Virginia, United States.