Gregorio married Catalina Muñoz Díaz ( Matos Aponte) on 11 Feb 1736 in Caguas, Puerto Rico, Province of Spain. Catalina (daughter of Manuel Valerio Muñoz Oneca and Gerónima Díaz Delgado (Muñoz Oneca), .) was born on 26 Dec 1716 in Caguas, Puerto Rico, Province of Spain; died about 1816 in Caguas, Puerto Rico, Province of Spain. [Group Sheet] [Family Chart]

1. Micaela Matos Muñoz was born in UNKNOWN; died in UNKNOWN.
2. Josefa Matos Muñoz was born about 1744 in Caguas Puerto Rico, Province of Spain; died in UNKNOWN.
3. Juan Matos Muñoz was born in Aug 1748 in Caguas Puerto Rico, Province of Spain; died in UNKNOWN.